Lyophilization Equipment and Process Consulting

Examples of Services Provided:  Mr Milligan has decades of experience with lyophilizer selection, purchase, installation, qualification and daily operation of this complex technology.  Specializing in auto load/unload technology and barrier technology justification and optimization .

• Equipment selection, user requirements specifications, request for quotation, and equipment specification.
• Working with specialized contractors supporting cycle development and optimization of lyophilization cycles.
• Scale-up issues.
• Capping after lyophilization.
• Facility expansion layouts & equipment design.
• Equipment, facility and utility qualification, and process validation.
• Container Closure Integrity (CCIT) studies using state-of-the-art near infra red laser technology to include 100% inspection of the processed batch.
• Media fill strategy.
• Stoppers sticking to lyo chamber shelves.
• Leak detection and silicone leak detection.

photo supplied by GEA group